Science as a human creation and endeavor. No humans, no science. Of course, Nature, the universe, the material world--whatever term you prefer--exists independently of any human being. And events and processes occur whether humans identify them or not. Science is the human effort to understand the natural world by using empirical observation and (mostly) mathematical modeling. But whatever conclusions we reach are reached by we fallible humans. Based on this fundamental premise of human fallibility, all our knowledge of "science" is in some measure hypothetical, tentative. Some conclusions are now beyond serious dispute (e.g., the earth orbits the sun) but a great deal of what we call "science" is simply our best effort to arrive at what we should consider a tentative conclusion. And when we move away from relatively mechanical systems (e.g., the orbits of the solar system) into complex systems, such as those of biology, which are neither mechanical nor fixed (unchanging), we are in a much more difficult arena in which to navigate. Thus, when we speak of science, especially concerning the biology of viruses, human health, or vaccines (to provide only three topical examples), we don't have "Science" that provides us with infallible answers, but only fallible science as an ongoing endeavor to attempt to drive away falsehood while at the same time allowing us to act with some sense of rationality (matching our actions to intended ends).
Thus, if I refer to "science" in support of everyone wearing a mask in public (as I do), I'm not appealing to an infallible writ from on high, but to the most persuasive conclusions based on the best evidence upon which we can base our actions. All that may change--and will undoubtedly change--as we learn more from gathering new facts and forming new models. Indeed, at the beginning of the pandemic, masks for Americans were discouraged, although the recommendations seem to have been based more upon problems of human behavior (hoarding, decreased risk aversion) rather than recommendations based realities of viral transmission. But in any event, "science" seems to have changed its mind, as well it should. This isn't a shortcoming of science, it's the essence of its strength and utility.
So, based on the best available scientific knowledge and conclusion (tentative though they may be), WEAR THE DAMNED MASK! And when (assuming here) a vaccine arrives, make the best possible decision based upon the best available evidence. Understand that every human act entails an element of risk. Every action is an experiment of sorts and will entail unintended consequences. But this is a part of the human condition. Acknowledge our predicaments and dilemmas and act accordingly.